Nutritional Genetics Frequently Asked Questions


Do not radically alter your diet or lifestyle without first consulting a doctor or specialist.

How can understanding your genes give you a longer, healthier life?

How can understanding your genes give you a longer, healthier life?
Your health is a result of interactions between your genes and lifestyle factors such as diet, exercise, stress, smoking and alcohol. It is your genetic make-up that determines which nutrients are used and how they are used; the way toxins are removed, what happens to any waste products and how efficient and effective these key processes are within the body. However, by adjusting your lifestyle, you can have a great impact on how your genes work and compensate for areas in which your genes are not functioning at an optimal level.

Does this test offer any benefit that I wouldn't get if I followed all the good advice from healthcare professionals, research organizations, or medical literature?
Even if you follow all of this advice to the letter, it is still worth knowing your genetic profile. In particular, the people who will find the service to be of considerable value are those who need an extra bit of motivation to maintain healthy habits, or those who find it easier and more realistic to focus on areas particularly important for them - while still being able to indulge (in moderation!) in some dietary or lifestyle preferences.

What kind of genetic screening does is performed?
The screening focuses only on gene variations that call for changes in diet or lifestyle. By learning about the specific nature of some of your genes from your Advisory Report, you will discover how to avoid the things that have a negative impact on your metabolism and learn to focus on factors that are of greatest benefit to your health. Our DNA analysis does not include genetic diseases that are not influenced by nutrition and lifestyle.

Are gene variations always bad?
No, not at all. Most of the time, gene variations have no effect on our body systems or our health, and in certain cases these variations can even be beneficial. However, sometimes a variation can make the gene send a slightly 'wrongly worded' message to the cell. Upon receiving the garbled message, the cell will manufacture a product - such as an enzyme - that doesn't work exactly as it should; the variant enzyme may, for example, work faster or more slowly than is best for the body. Combined with an unhealthy diet or lifestyle, such a gene variation may make a person more susceptible to developing illnesses.

If I have variations in my genes, can these be corrected?
Genes are found in every cell of the body. Therefore, for the correction to be effective, scientists must find a way to reach every single cell. This is an enormous challenge for gene therapy, an experimental procedure that is attempted only in serious genetic diseases caused by a single defective gene, such as cystic fibrosis. In contrast, the variations screened for by Genelex are fairly common in the general population, and their presence does not mean you will definitely become ill. It would thus be both impractical and inappropriate to attempt to physically 'correct' these commonly occurring variations - even if the technology existed to make this possible. Genelex is not involved in researching gene therapy, and we do not offer treatment of any kind. Rather, we provide advice that takes into account the presence of genetic variations. Our service allows you to maintain good health by following dietary and lifestyle advice tailored to your unique genetic profile.

Will anyone outside your company have access to my DNA results or questionnaire?
No, both your DNA results and your questionnaire will be kept strictly confidential. We take the utmost care to safeguard your privacy, and personally identifiable information will never be disclosed. In particular, we do not provide information to insurance companies. Once you put the coded label on your DNA sample, your DNA is identifiable only by that label and even members of Genelex's lab staff do not know to whom the sample belongs. When the analysis has been completed, the sample is physically destroyed while the anonymous DNA record is stored for research purposes only. We do, however, keep your contact information separately in our databases for further communication with you. Please note that if a practitioner has ordered the test on your behalf, the results will be sent to that practitioner.

Will you decode my complete genome?
Decoding a complete genome is a massive task. The Human Genome Project has mapped and deciphered the complete genomes of only a few individuals, and this has taken many years of work and an international network of research centers to accomplish. We are lucky to be able to benefit from what has been discovered in this complex and exciting project, and we can deliver some of the benefits directly to customers like you in a simple, rapid and economical service. We examine only a relatively limited number of specific sections of the whole genome - sections known to code for metabolic enzymes that are crucial to long-term health and well-being.

Can the test tell me if I will develop a serious inherited illness, such as Huntington's disease?
No, we don't screen for inherited disorders that are not affected by diet and lifestyle, such as Huntington's disease. These disorders, known as single-gene diseases because they are caused by a defect in only one gene, are relatively rare. People with a family history of such an illness are likely to be already receiving counseling and support within the health service system. If you think you may be at risk for an inherited disease, you should speak to your doctor.

Genelex's screen is relevant only for the much more common 'complex' diseases such as heart disease and cancer. In most cases these diseases are not linked to one specific gene; rather, your risk of developing them is part of a complicated equation that involves numerous genes and lifestyle factors. While we cannot promise that if you take our advice you will never become ill, we provide you with a 'zebra crossing' for your health, allowing you to make informed choices about your diet and lifestyle that give you a better chance of staying well.

Will the testing be able to tell me whether I am ill?
No, we can only determine what type of genes people have and how they relate to certain metabolic factors involved in well-being. In nearly all cases, these genes will be the same whether a person is well or ill. This is why we ask you in the lifestyle questionnaire whether you are under medical supervision. If you think you may be ill, you should consult your doctor.

What should I do if I have questions about my results or require further information?
In the first instance, you should ask your physician or nutritionist. If you require further information, you can contact us directly.

Where do I turn for further nutritional counseling?
If you would like to receive further nutritional guidance after reading your personal report, you should consult a dietitian, nutritionist or your doctor. We have created a directory of these specialists for your convenience. This may be particularly valid if you have been diagnosed with a food intolerance, an allergy or any medical condition - or if you simply wish to continue learning about healthy eating and lifestyle habits.

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Founded in 1987, Genelex Corporation is accredited by the American Association of Blood Banks (AABB)Parentage Testing Committee in DNA parentage testing since 1992 and is Washington State Medical Test Site No. MTS-3919 CLIA No. 50D0980559. Genelex was accredited by the American Society of Crime Laboratory Directors Laboratory Accreditation Board (ASCLD LAB) in forensic DNA testing from 1998-2003 and has contributed to the validation of National Institute of Standards and Technology (NIST) Standard Reference Materials.

 
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